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EV-C@p is a High relevance “Agrofood for biotech e biopharmaceuticals” project supported in part by the Italian Ministry of Foreign Affairs and International Cooperation”, grant number KR23GR03. Objectives of EV-C@p are trifold: 

  • scientifically relevant results as foreseen in the proposal 
  • contribute to the development of the international cooperation between South Korea and Italy
  • Train young researchers  

The scientific objectives of EV-C@p are centered on the development of new systems for molecular delivery by exploiting plant derived extracellular vesicles and nanovesicles for molecular encapsulation. Within this project researchers from IBBR-CNR and the Korean Kyung Hee university will setup methodology to produce EVs from tomatoes and korean red ginseng and their cell suspension cultures. 

2nd EVIta Symposium

Fianly, EVs and MS laboratory could participate in a face-to-face meting. We went to Ciocco Resort close to Barga for the 2nd EVIta Symposium in 20-22nd of September 2021. It was a great occasion to immerse in the extracellular vesicle world in the heart of the fascinating Serchio Valley, a mysterious part of Tuscany with a fantastic view. There were more than 150 participants!

 

At the pre meeting on September the 20th, Dr. Gabriella Pocsvalvi showcased two of our latest international projects, greenEV and mEVChip. Dr. Mannea Moubarak from Damanhur University, Egypt, has been working in our group for two years on greenEV, focusing on the innovative production of extracellular vesicles from plant cells. The project is funded by the Horizon 2020 Marie Skłodowska-Curie Action. In the mEVChip project, we aim to develop a microfluidic chip to assess the anti-inflammatory effect of ginger derived extracellular vesicles in cells with the collaboration of CINVESTAV. This project is financed by the Center for Research and Advanced Studies of the National Polytechnic Institute of the United Mexican States (Cinvestav) and the National Research Council of Italy (CNR).

 

On September 21st, Ramila Mammadova, Ph.D. student at EVs and MS laboratory gave a talk on the “Identification of viral particles copurifying with tomato-derived nanovesicles by shotgun proteomics”, as part of the oral presentation program. She reported one of our latest findings on how we identified different tomato viruses in nanovesicles samples. This piece of research is the continuation of our recently published work on tomato fruit NVs.

On September 21st, Ana Paulina Ramos Juarez, Ph.D. student at EVs and MS laboratory, presented our work on the topic of biomarker discovery using plasma-derived EVs in the poster section. The poster is entitled “Optimization of gradient ultracentrifugation for the isolation of different subpopulations of extracellular vesicles from plasma”. Since the isolation of plasma EVs is very tricky, there was a big interest in this presentation. Please download the poster from here.

 

On September 22nd Dr. Gabriella Pocsvalvi had the opportunity to chair the session “EV biomarkers and therapeutics” where different groups from all over the country showed their latest findings on this topic.

 

These were busy days full of interesting information and novel topics. We were pleased to see so much interest in the field we are involved and the willingness of all to collaborate in advancing it. For Ramila, it was the first time that she talked in front of such a big audience. We are glad to had this opportunity to meeting in person with colleges from Italy and abroad. A special thanks to the organizers of the event, EVIta committee and the world-renowned scientists who presented keynote lectures and shared with us their knowledge and the staff for taking care of everything. We hope to meet all again soon and stay tuned to our news for more information.

Christopher Stanly leaves EVs-MS and heads for a new position

31/08/2021

We said arrivederci to Chris after he finished his Post. doc. research stay in Napoli. We went for dinner at Santa Lucia, where Chris sang 'O sarracino. It was a magic night! We will miss you SARRRACINO!

These are his words:

 "I was a postdoctoral Research Fellow in the “VES4US” project. I spent three wonderful years as a postdoc fellow working in the same lab where I completed my Ph.D. and, will always be grateful for the support I received from Gabriella, Imma, and my fantastic lab mates. I believe the experience I gained during my stay in Naples at “Extracellular Vesicles and Mass Spectrometry Laboratory” will help me achieve my goal of establishing myself as a successful researcher. Looking forward to finding answers to the unknown.

-Chris"

CNR-EV-NET: Joining forces in the study of Extracellular Vesicles

28/04/2022

 A hybrid, online and face-to face event was organized at the central CNR headquarter (Aula Marconi), Piazzale Aldo Moro 7, Roma. 


The scientific community of the National Research Council (CNR) organized a day dedicated to Extracellular Vesicles (EVs), a scientific field that crosses different departments and involves multiple strategic areas, with the aim of stimulating discussion and consolidate skills accumulated over the years within the CNR laboratories. The aim was to create an interdepartmental network for the study and application of Extracellular Vesicles within CNR, named CNR-EV-NET. This was also the title of the workshop 'CNR-EV-NET: Joining forces in the study of Extracellular Vesicles' held in Rome, at the CNR headquarter (Aula Marconi) on April 28, with the hybrid participation both in person and online streaming.

The proponents of CNR-EV-NET are researchers from six institutes of four CNR departments: Antonella Bongiovanni of the Institute for Biomedical Research and Innovation (Cnr- Irib, DSB); Marcella Chiari and Marina Cretich of the "Giulio Natta" Institute of Chemical Sciences and Technologies (Cnr-Scitec, DSCTM); Mauro Manno of the Institute of Biophysics (Cnr-Ibf, DSFTM); Gabriella Pocsfalvi of the Institute of Biosciences and Bioresources (Cnr-IBBR, DISBA); Francesco Valle and Marco Brucale of the Institute for the study of nanostructured materials (Cnr-ISMN, DSCTM); Claudia Verderio of the Institute of Neuroscience (Cnr-IN, DSB).

In addition to the stimulating an interactive discussion during the event, the proposing group aspires to the establishment of a CNR network of researchers active on the extracellular vesicles research field. Two experts, Edit Buzas (president of the international society of extracellular vesicles - ISEV) and Benedetta Bussolati (president of the Italian society for extracellular vesicles - EVIta), gave talk during the workshop. They underlined the importance of the basic research on EVs in order to exploit their potential applications in various applied research fields including precision medicine. The afternoon session was dedicated to discussions with the community operating in the field by animating a discussion aimed at identifying the key elements to be represented in the founding acts of the interdepartmental network.

From EVs-MS lab Gabriella Pocsfalvi was present et the workshop. She introduced Edit Buzas to the audience.

 

Logo proposto per l'evento e la costituenda rete scientifica elaborato da Alessandro Gori

 

Where we are

Address:

EVs & MS laboratory

Institute of Biosciences and BioResources

National Research Council

via P. Castellino, 111

80131, Napoli

ITALY

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