Plant-derived vesicles​

Plant-derived EVs

EVs represent a new paradigm in medicine and biology due to their ability to carry and transfer a complex functional biological material that compresses proteins, RNAs, lipids, and metabolites to recipient cells. The role of EVs in intercellular, interspecies, and interkingdom communications is increasingly recognized today. Similar to a mammalian cell, intra and extracellular vesicles of a plant cell are involved in many physiological processes, including transport and defense. At EVs & MS lab we have consolidated experience in the extraction of nanovesicles from different plant materials. So far, we have extracted nanovesicles (NVs) from
  • Citrus species
  • Tomato fruit, leaves, and root exudate
  • Coconut water
  • Feijoa sellowiana fruit
  • Grapes
  • Strawberry
  • Ginger root
  • Cucumber
  • Apple
  • Pomegranate
At EVs & MS lab, these innovative biomaterials are under exploitation for human health due to their anti-inflammatory, anticancer, and tissue regenerative properties, as well as to their valuable impact on the gut microbiome. Moreover, EV-like structures from edible plants were isolated with the aim to transform them into vectors for various applications including drug, nutraceutical, and cosmeceutical delivery.
Our recent study at EVs & MS shows that EVs released by plant roots show antifungal activity by carrying a complex protein toolset for plant resistance.

At EVs & MS we are developing a novel class of molecular delivery vectors for human health and next generation organic farming by building on the natural delivery capabilities of nanovesicles.

Where we are


EVs & MS laboratory

Institute of Biosciences and BioResources

National Research Council

via P. Castellino, 111

80131, Napoli


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